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KMID : 1102220160350040252
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Kidney Research and Clinical Practice
2016 Volume.35 No. 4 p.252 ~ p.254
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Acute interstitial nephritis induced by Solanum nigrum
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Oh Sung-Sik
Choi Myung-Woo
Choi Mi-Rim
Lee Jong-Hwa
Yang Hyun-Ju
Choi Yeong-Jin
Cho A-Young
Lee Kwang-Young
Sun In-O
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Abstract
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Acute interstitial nephritis (AIN) is an important cause of reversible acute kidney injury and pathologically characterized by inflammatory infiltrate in the renal interstitium. Solanum nigrum (S. nigrum) is a medicinal plant member of the Solanaceae
family. Although S. nigrum has been traditionally used to treat various ailments such as pain, inflammation, and fever, it has also been reported to have a toxic effect, resulting in anticholinergic symptoms. However, there have been no reports of AIN caused by S. nigrum. Here, we report the first case of biopsyconfirmed AIN after ingestion of S. nigrum. The patient was successfully treated using corticosteroid therapy.
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KEYWORD
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Acute interstitial nephritis, Corticosteroid, Solanum
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